Precautions and Warnings With Travoprost

Before starting treatment, talk to your healthcare provider about precautions and warnings with travoprost to help ensure a safe treatment process. You should also let him or her know if you are pregnant, have an inflammatory eye condition, or have any allergies before using travoprost. Warnings and precautions also apply to people who are allergic to any components used to make the medication.

What Should I Tell My Healthcare Provider Before Using Travoprost?

You should talk with your healthcare provider prior to using travoprost ophthalmic solution (Travatan®) if you:
  • Have any allergies, including allergies to food, dyes, or preservatives
  • Have an inflammatory eye condition, such as iritis or uveitis
  • Are pregnant or thinking of becoming pregnant
  • Are breastfeeding.
Make sure to tell your healthcare provider about all other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Specific Warnings and Precautions With Travoprost

Warnings and precautions to be aware of prior to taking travoprost include the following:
  • The medication can cause increased pigmentation (darkening) of certain tissues. It can cause a darkening of the iris (the colored part) of the eyes, the eyelids, and the eyelashes. While darkening of the eyelids and eyelashes usually improves after travoprost is stopped, eye darkening is usually permanent. This eye darkening is most noticeable in people with light-colored eyes (such as blue eyes), as the medication tends to make the eyes more brown. These changes are not dangerous, and you can keep taking travoprost if they occur.
  • There have been reports of macular edema (swelling of the macula of the eye) in some people who took eyedrops similar to travoprost. Be sure to let your healthcare provider know if you have any vision changes, as they may be a sign of macular edema.
  • Travoprost can also cause longer and thicker eyelashes, as well as eyelashes that grow in wrong directions.
  • There have been a few cases of bacterial keratitis (a dangerous infection of the cornea of the eye that can quickly lead to blindness) in people who use eyedrops. These cases were caused by accidental contamination of the bottle by the users, who usually already had some damage or disease of the cornea. It is very important to prevent contamination of the bottle. Never touch the tip of the bottle with your eye, hands, or any other surfaces.
  • Travoprost is not approved for angle closure glaucoma, inflammatory glaucoma, or neovascular glaucoma, as it has not been thoroughly studied for these types.
  • Make sure your healthcare provider knows if you have a history of iritis or uveitis (certain inflammatory conditions of the eye). In general, travoprost should be avoided if you currently have eye inflammation.
  • If you develop any eye condition or require eye surgery, let your healthcare provider know. You may be advised to temporarily stop taking travoprost.
  • If you wear contact lenses, you must take them out before using the medication and wait at least 15 minutes before reinserting them.
  • Wait at least five minutes between using travoprost and any other eyedrops.
  • Travoprost can potentially interact with a few other medications (see Drug Interactions With Travoprost).
  • Travoprost is considered a pregnancy Category C medication. This means that it may not be safe for use during pregnancy, although the full risks are not currently known (see Travatan and Pregnancy).
  • It is unknown whether the medication passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Travatan and Breastfeeding).
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