Precautions and Warnings With Tafluprost

Safety precautions for tafluprost include warnings for people who have certain medical issues, including a history of inflammatory eye conditions or certain allergies. These eye drops can also cause reactions with certain other medicines. It is also important to tell your healthcare provider if you are pregnant or breastfeeding, as the full risks of using this medication during pregnancy or while breastfeeding are currently unknown.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to using tafluprost ophthalmic solution (Zioptan®) if you:
  • Have an inflammatory eye condition, such as iritis or uveitis
  • Have any allergies, including to foods, dyes, or preservatives
  • Are pregnant or thinking of becoming pregnant
  • Are breastfeeding.
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Specific Tafluprost Precautions and Warnings

Some warnings and precautions to be aware of prior to using these eye drops include the following:
  • Tafluprost can cause increased pigmentation (darkening) of certain tissues. It can cause a darkening of the iris (the colored part) of the eyes, the eyelids, and the eyelashes.

While darkening of the eyelids and eyelashes usually improves after tafluprost is stopped, eye darkening is usually permanent. This eye darkening is most noticeable in people with light-colored eyes (such as blue eyes), as tafluprost tends to make the eyes more brown. These changes are not dangerous, and you can keep using tafluprost if they occur.

  • Tafluprost can also cause longer and thicker eyelashes, as well as eyelashes that grow in the wrong directions.
  • There have been reports of macular edema (swelling of the macula of the eye) in some people who used tafluprost. Make sure to let your healthcare provider know if you have any vision changes, as they may be a sign of macular edema.
  • People with a history of iritis or uveitis (certain inflammatory conditions of the eye) should generally not use tafluprost. These eye drops should typically be avoided if you currently have eye inflammation.
  • Tafluprost is not approved for angle closure glaucoma, inflammatory glaucoma, or neovascular glaucoma, as it has not been thoroughly studied for these types of glaucoma.
  • If you develop any eye condition or require eye surgery, let your healthcare provider know. You may be advised to temporarily stop using tafluprost.
  • Wait at least five minutes in between using tafluprost and any other eye drops.
  • Tafluprost is a pregnancy Category C medication. This means that it may not be safe for use during pregnancy, although the full risks are currently unknown (see Zioptan and Pregnancy).
  • It is unknown if tafluprost passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to using the drops (see Zioptan and Breastfeeding).

Tafluprost Drug Information

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