What Is Ranibizumab Used For?

Using Ranibizumab for Retinal Vein Occlusion Macular Edema

Retinal vein occlusion (RVO) is a blockage in a vein in the retina of the eye. There are two types of RVO, branch RVO and central RVO. Blockage of retinal veins can cause various complications, including macular edema (fluid accumulation in the macula of the eye). This fluid accumulation can cause distortion and blurriness in the center of one's vision.
Ranibizumab is approved for the treatment of macular edema following retinal vein occlusion (including branch RVO and central RVO). It has been shown to help reduce further vision loss and to help many people regain lost vision. 

Using Ranibizumab for Diabetic Macular Edema

Eye problems are common among people with diabetes. Diabetes can cause blood vessels in the eye to become leaky, leading to fluid accumulation in the macula. This is known as diabetic macular edema and can occur with type 1 diabetes or type 2 diabetes.
Ranibizumab is approved for the treatment of diabetic macular edema. It has been shown to help reduce further vision loss and to help many people regain lost vision.

How Does Ranibizumab Work?

Wet macular degeneration is caused by abnormal blood vessel growth in the back of the eye. The blood vessels grow behind the retina, underneath the macula (a part of the retina that is essential for detailed vision). These new blood vessels are not normal and are weak and prone to leaking. Leaking causes damage to the macula, which causes "wet" macular degeneration.
Macular edema following retinal vein occlusion is caused by a blockage of a retinal vein, leading to the leakage of fluid.
Ranibizumab is part of an antibody that is designed to bind to and inhibit vascular endothelial growth factor (VEGF-A). VEGF-A is a naturally occurring protein that encourages blood vessel leakage and the growth of new blood vessels (including abnormal blood vessels). By binding to VEGF-A, ranibizumab prevents this protein from encouraging new blood vessel growth and blood vessel leakage. This helps to slow down (or even reverse) vision loss and macular damage.

Ranibizumab Injection for Macular Degeneration

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