Prolensa

A healthcare provider may prescribe Prolensa eye drops for use before cataract surgery. This medication is a type of nonsteroidal anti-inflammatory drug (NSAID), and it is used to reduce inflammation and pain. It is used the day before your surgery and used once a day for 14 days after surgery. Possible side effects may include eye pain and sensitivity to light.

What Is Prolensa?

Prolensa™ (bromfenac ophthalmic solution) is a prescription medication used to reduce inflammation and pain after cataract surgery. It belongs to a group of medicines known as nonsteroidal anti-inflammatory drugs, or NSAIDs for short.
 
(Click Prolensa Uses for more information on this topic, including possible off-label uses.)
 

Who Makes It?

Prolensa is made by Bausch & Lomb Incorporated.
 

How Does Prolensa Work?

As mentioned previously, Prolensa belongs to a group of medications called nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs work by blocking an enzyme known as cyclooxygenase (COX). The COX enzyme is responsible for the production of substances in the body known as prostaglandins.
 
Prostaglandins have a variety of functions in the body. One of their roles is to activate an inflammatory response, including inflammation in the eye, as well as cause pain. By blocking the production of prostaglandins, Prolensa reduces inflammation and pain.
 
Prolensa is given as an eye drop, and works directly in the eye. Very little, if any, of the drug is absorbed from the eye into the body with normal use.
 

Clinical Effects

In clinical studies, Prolensa was shown to reduce pain and swelling following cataract surgery. In these studies, people who were going to have cataract surgery were given either Prolensa or a placebo (an eye drop with no active ingredient) to use starting one day before surgery, the day of surgery, and for 14 days after surgery. Researchers then looked at how many people had eye inflammation and pain 15 days after their surgery.
 
In these studies, 45.5 percent of those using Prolensa were inflammation-free 15 days after surgery, compared with 24.1 to 30 percent of those using the placebo. In addition, up to 81.3 percent of people using Prolensa reported no pain after 15 days, compared with up to 55.5 percent of those using the placebo.
 
 

Prolensa Medication Information

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