Ocupress and Pregnancy
In studies on pregnancy and Ocupress (carteolol), the medication increased the risk of miscarriages and low fetal weight when it was given in high doses (by mouth) to pregnant rats and rabbits. However, it is important to know that animals do not always respond to medicines the same way that humans do. If you are taking this drug and pregnancy occurs, notify your healthcare provider immediately.
Ocupress® (carteolol hydrochloride) is a beta blocker eye medication approved for the treatment of high eye pressure and open angle glaucoma. It is available by prescription only. It is not known if this medication is safe for use during pregnancy. Animal studies indicate that Ocupress could potentially be harmful to a developing fetus.
The U.S. Food and Drug Administration (FDA) uses a pregnancy category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that have not been studied in pregnant humans but do appear to cause harm to the fetus in animal studies. Also, medicines that have not been studied in any pregnant women or animals are automatically given a pregnancy Category C rating.
Ocupress was given a pregnancy Category C rating because of problems seen in animal studies. Giving extremely high doses of Ocupress by mouth to pregnant rats and rabbits increased the risk of miscarriages, low fetal weight, and "wavy" ribs. It should be noted that these doses were high enough to cause toxicity in the mother animals as well.
It is important to note that animals do not always respond to medicines in the same way that humans do. Therefore, a pregnancy Category C medicine may be given to a pregnant woman if the healthcare provider believes that the benefits to the pregnant woman outweigh any possible risks to the unborn child.