Mitomycin Trabeculectomy Dosing

Mitomycin ophthalmic (Mitosol®) is a medicine used during glaucoma surgery, such as a trabeculectomy. During this type of surgery, a surgeon creates a tiny opening in the eye that allows fluid to flow out, thus lowering eye pressure. Mitomycin ophthalmic is applied on the surgical site to help prevent new cell growth and scarring that could cause the procedure to be unsuccessful.
When used for a trabeculectomy, the dosing guidelines for mitomycin ophthalmic call for one vial (0.2 mg) of the powder to be dissolved in 1 mL of sterile water. This liquid is then applied topically to the surgical site using sponges. The sponges are normally kept in place for two minutes and then removed.
(For more information, click Mitomycin Ophthalmic Dosage. This eMedTV article provides specific dosing guidelines for this eye medication, as well as several important tips for safely and effectively using it.)
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