Mitomycin-C Concentration for Ophthalmic Surgery

Mitomycin ophthalmic (Mitosol®) is a medication prescribed for use during glaucoma surgery. The active ingredient in the medication, mitomycin, is sometimes referred to as mitomycin-C.
Mitomycin ophthalmic belongs to a general group of medicines known as antineoplastic antibiotics. It works by interfering with how DNA replicates. This helps to prevent new cell growth at the surgical site, which prevents scarring that could make glaucoma surgery unsuccessful.
When used for glaucoma surgery, the dosing concentration of mitomycin-C is 0.2 mg of the powder (one vial) to be dissolved in 1 mL of sterile water. A healthcare provider will apply this medicine as a single, one-time dose to the surgical site by first saturating sponges with the medicine and then applying the sponges to the surgical area on your eye. The sponges are normally kept in place for two minutes and then removed.
(Click Mitomycin Ophthalmic Dosage for more details on how this medication is used. It also provides information on what to expect during treatment.)
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