Eyes Home > Ranibizumab Dosing

When treating wet macular degeneration or RVO macular edema with ranibizumab, dosing guidelines call for a specific amount to be injected into the affected eye. The typical amount is 0.5 mg once a month. Before the injection, your eye(s) will be cleansed and numbed. After administering your monthly ranibizumab dosage, your healthcare provider will observe you for a while to make sure you do not develop any serious side effects.

Ranibizumab Dosing: An Introduction

The dose of ranibizumab (Lucentis®) that your healthcare provider recommends will vary, depending on a number of factors, including:
  • The condition being treated
  • How you respond to ranibizumab
  • Other medications you may be taking
  • Other medical conditions you may have.
As is always the case, do not adjust your ranibizumab dose unless your healthcare provider specifically instructs you to do so.

Ranibizumab Dosing for Wet Macular Degeneration or RVO Macular Edema

The recommended dose of ranibizumab for the treatment of wet macular degeneration or for the treatment of macular edema due to retinal vein occlusion (RVO) is 0.5 mg, injected into the eye once a month (about every 28 days). If only one of your eyes has the disease, you will receive a dose just in that eye. If both your eyes are affected, you will receive a dose in each eye.
In studies, people who received ranibizumab injections once a month had more vision improvement, compared to people who received injections less often. However, there may be certain situations in which your healthcare provider recommends using injections less frequently than once a month. In these situations, after the first four once-a-month doses, doses are usually given once every three months. 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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