Eyes Home > Precautions and Warnings With Pegaptanib

Being aware of the precautions and warnings with pegaptanib can help minimize risks and ensure your safety. Prior to taking it, tell your healthcare provider if you have any allergies or infections in or around the eyes. Precautions and warnings with pegaptanib include being aware that the injections may cause a temporary increase in the pressure inside the eye and retinal detachment is a rare but possible complication.

Pegaptanib: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking pegaptanib sodium (Macugen®) if you have:
  • An infection in or around the eyes
  • Any allergies, including allergies to food, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
Make sure to tell your healthcare provider about all other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Specific Precautions and Warnings With Pegaptanib

Warnings and precautions to be aware of prior to taking pegaptanib include the following:
  • As with any injection into the eye, pegaptanib can cause retinal detachment or other eye problems (although these are rare). Retinal detachment is very serious and can lead to blindness. Your healthcare provider should monitor you closely to make sure you do not develop such problems. Let your healthcare provider know if you have any of the following side effects, which may be signs of serous problems:
    • Eye redness
    • Sensitivity to light
    • Vision changes.
  • Sometimes, pegaptanib injections can cause a temporary increase in the pressure inside the eye. Your healthcare provider should monitor your eyes immediately after each injection to make sure that the pressure in your eye is not too high.
  • Pegaptanib is unlikely to interact with other medications (see Drug Interactions With Pegaptanib).
  • Pegaptanib is considered a pregnancy Category B medication. This means that it is probably safe for use during pregnancy, although the full risks are not known. Talk to your healthcare provider about the risks and benefits of using the drug while pregnant (see Macugen and Pregnancy).
  • It is not known if pegaptanib passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Macugen and Breastfeeding).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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