Eyes Home > Mitomycin Ophthalmic

Available by prescription only, mitomycin ophthalmic is used on the eye during glaucoma surgery. A healthcare provider will apply this medicine on the hole created during surgery to help prevent new cell growth. There is only one standard dosage of this medicine, and it is applied just once. Side effects are possible and may include cataracts, inflammation, and infections.

What Is Mitomycin Ophthalmic?

Mitomycin ophthalmic (Mitosol®) is a prescription medication approved for use during glaucoma surgery. It belongs to a general group of medicines known as antineoplastic antibiotics.
The active ingredient in the medication, mitomycin, is sometimes referred to as mitomycin-C. It is also available in an intravenous (IV) injectable form. Injectable mitomycin is approved to treat stomach or pancreatic cancer.
(Click What Is Mitomycin Ophthalmic Used For? for more information on this topic, including possible off-label uses.)

Are There Side Effects?

Just like any medicine, mitomycin ophthalmic may cause side effects. However, not everyone who uses the drug will experience problems. In fact, most people tolerate it quite well.
If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious reactions are less common.
The most common side effects of mitomycin ophthalmic may include but are not limited to:
  • Bleb leak (a bleb is a small, fluid-filled bubble that forms over the eye following glaucoma surgery) 
  • Infection
  • Inflammation
  • Low pressure within the eye
  • Cataracts.
(Click Mitomycin Ophthalmic Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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