Eyes Home > Precautions and Warnings With Dorzolamide

Before starting treatment with dorzolamide, let your healthcare provider know if you have kidney disease, liver disease, or any allergies. These eye drops are not suitable for everyone, and they have not been studied adequately in people with kidney or liver problems. Other dorzolamide precautions and warnings apply to people who wear contact lenses and women who are pregnant or breastfeeding.

What Should I Tell My Healthcare Provider?

Prior to using dorzolamide hydrochloride (Trusopt®), tell your healthcare provider if you have:
  • Liver disease, such as liver failure, cirrhosis, or hepatitis
  • Kidney disease, such as kidney failure (renal failure)
  • Any allergies, including to food, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Specific Dorzolamide Warnings and Precautions

Precautions and warnings to be aware of prior to using these dorzolamide include the following:
  • Dorzolamide is a sulfonamide ("sulfa" drug) and can cause serious allergic reactions in people allergic to such medications.
  • This medication has not been adequately studied in people with liver or kidney problems. It is not recommended for people with severe kidney problems and should be used with caution in people with liver problems.
  • If you wear soft contact lenses, be sure to remove them before each dorzolamide dosage and wait at least 15 minutes before reinserting them. This drug contains a preservative (benzalkonium chloride) that can bind to soft contact lenses.
  • Dorzolamide can potentially interact with some other medications (see Drug Interactions With Dorzolamide).
  • If you will be having eye surgery or develop any other eye problems or conditions (such as an infection), check with your healthcare provider about whether you should continue to take this medication.
  • If you use other eye drops, be sure to separate your dose of dorzolamide and your dose of the other drops by at least 10 minutes.
  • Dorzolamide is considered a pregnancy Category C medication. This means that it may not be safe for use during pregnancy, although the full risks are not currently known (see Trusopt and Pregnancy).
  • It is unknown if dorzolamide passes through breast milk in humans. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Trusopt and Breastfeeding).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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