Eyes Home > Drug Interactions With Dorzolamide/Timolol

If other beta blockers, other eye drops, methacholine, or several other drugs are taken with dorzolamide/timolol, interactions are possible. These reactions can be quite serious, causing low blood sugar, a decreased heart rate, and increased risk for stroke. In order to prevent such problems, your healthcare provider may adjust your medication regimen or monitor you more closely.

An Overview of Dorzolamide/Timolol Interactions

Dorzolamide/timolol (Cosopt®) can potentially interact with several other medications. Some of the drugs that may lead to interactions with dorzolamide/timolol include:
  • Other eye medications
  • Reserpine
  • Salicylates, such as:
    • Aspirin (Ecotrin®, Bayer®, Anacin®)
    • Bismuth subsalicylate (Pepto-Bismol®)
    • Choline magnesium trisalicylate (Trilisate®)
    • Diflunisal (Dolobid®)
    • Salsalate (Salflex®, Disalcid®, Amigesic®).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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