Eyes Home > Dorzolamide/Timolol

People with glaucoma or other eye conditions may find dorzolamide/timolol useful for their situation. This combination drug, which is applied to the affected eye twice daily, reduces the amount of fluid the eye produces, which in turn causes pressure in the eye to decrease. Common side effects include a bitter or unpleasant taste in the mouth, eye redness, and a stinging sensation in the eye.

What Is Dorzolamide/Timolol?

Dorzolamide/timolol (Cosopt®) is a prescription eye drop. It contains two different active ingredients: a carbonic anhydrase inhibitor (dorzolamide) and a beta blocker (timolol). It is approved to treat high eye pressure in people with chronic open-angle glaucoma or ocular hypertension.
(Click What Is Dorzolamide/Timolol Used For? for more information on this topic, including possible off-label uses.)

Potential Side Effects

Just like any medicine, dorzolamide/timolol can cause side effects. However, not everyone who takes the drug will experience problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious reactions are less common.
In clinical studies, the most common side effects seen with this medication included:
  • Bitter, sour, or unusual taste in the mouth
  • Eye burning or stinging.
(Click Side Effects of Dorzolamide/Timolol to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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