Brinzolamide belongs to a group of drugs called carbonic anhydrase inhibitors. Carbonic anhydrase is an enzyme found in many places throughout the body, including the eye. By inhibiting this enzyme, brinzolamide lowers the eye pressure by decreasing the amount of fluid produced by the eye (known as aqueous humor).
Can Children Use It?
Brinzolamide is not approved for children. This does not mean that children cannot use brinzolamide or that a healthcare provider cannot prescribe this medication for children. It simply reflects the fact that brinzolamide has not been shown to be effective in children. One study (in which a lower-than-typical brinzolamide dosage was used) failed to show that brinzolamide was effective in lowering eye pressure in children age four weeks to five years old.
Are There Off-Label Reasons to Use Brinzolamide?
On occasion, your healthcare provider may recommend brinzolamide for something other than high eye pressure or open-angle glaucoma (this would be known as an "off-label" use). At this time, using brinzolamide to treat acute angle-closure glaucoma would be an off-label use.
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