Ketotifen

Ketotifen is an eye medication approved for treating itchy eyes due to eye allergies. It is available over the counter and comes in the form of eye drops that are applied to each eye twice a day. The medicine, which belongs to a group of allergy medications known as antihistamines, works by blocking H1 receptors and decreasing the release of histamine from cells in the body.

What Is Ketotifen?

Ketotifen fumarate ophthalmic solution (Alaway®, Zaditor®, Zyrtec® Eye Drops, Claritin® Eye) is a nonprescription eye drop used to temporarily relieve itching due to eye allergies (known medically as allergic conjunctivitis).
 
(Click What Is Ketotifen Used For? for more information, including possible off-label uses.)
 

Potential Side Effects

As with any medicine, ketotifen can cause side effects. However, not everyone who takes the drug will experience bothersome side effects. Most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or can easily be treated by you or your healthcare provider. Serious side effects are less common.
 
Possible side effects of ketotifen include, but are not limited to:
 
  • Red eyes
  • Headaches
  • Stuffy or runny nose.
     
(Click Side Effects of Ketotifen to learn more, including potentially serious side effects that you should report immediately to your healthcare provider.)
 

What Should I Tell My Healthcare Provider Before Taking Ketotifen?

You should talk with your healthcare provider prior to taking this medication if you:
 
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 
(Click Precautions and Warnings With Ketotifen to learn more, including information on who should not take the drug.)
 

How Does the Drug Work?

Ketotifen belongs to a group of allergy medications known as antihistamines. Specifically, it is an H1 receptor antagonist. This means that it blocks a specific type of histamine receptor in the body (known as H1 receptors). Since the symptoms of allergic reactions are partly caused by histamine, ketotifen can help prevent or relieve allergy symptoms.
 
In addition to blocking histamine receptors, this medication also seems to decrease the release of histamine from cells in the body and may also inhibit other substances (such as leukotrienes or eosinophils) produced by the body in response to an allergen.
 

When and How to Take Ketotifen

General considerations include the following:
 
  • This medication comes in the form of an eye drop. It is used in each eye twice a day.
     
  • If you wear contact lenses, you must remove them to use the drops. In order to prevent the lens from absorbing the preservatives in the medication, be sure to wait at least 10 minutes after using the drops before reinserting the lens. Do not wear your contact lenses if your eye is still red.
     
  • In order to prevent contamination of the drops, do not touch the tip of the dropper to any surface, including the surface of the eye.
     
  • For the medication to work properly, it must be taken as directed.
     

Dosing Information

There is only one standard recommended dosage for this product. As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
 
(Click Ketotifen Dosage for more information.)
 

Ketotifen Drug Interactions

Ketotifen eye drops are probably unlikely to interact with other medicines (see Drug Interactions With Ketotifen).
 

What If I Take an Overdose?

It is not clear exactly what to expect from an overdose with this medication. If you happen to overdose on this medication, seek immediate medical attention.
 
(Click Ketotifen Overdose for more information.)
 

How Should Ketotifen Be Stored?

Ketotifen eye drops should be stored at room temperature. Keep this and all other medications out of the reach of children. Be sure to put the cap back on after each use.
 

What Should I Do If I Miss a Dose?

If you do not take your ketotifen as scheduled, take your missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose.
 

Generic Availability for Ketotifen

This medication is available in generic form (see Generic Alaway, Generic Zaditor, Generic Zyrtec Eye Drops, or Generic Claritin Eye for more information).
 

Who Makes This Medication?

Zaditor is manufactured by Novartis Pharmaceuticals Corporation, and Alaway is made by Bausch and Lomb. Zyrtec Eye Drops is made by McNeil Consumer Healthcare, and Claritin Eye is made by Schering-Plough HealthCare Products, Inc. Generic versions are made by various different manufacturers.
 

Ketotifen Strengths

Ketotifen eye drops come in one strength -- ketotifen 0.025%, equivalent to 0.035% ketotifen fumarate.
 
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