Drug Interactions With Dorzolamide
Other Carbonic Anhydrase Inhibitors
Dorzolamide is a carbonic anhydrase inhibitor. Even though it is an eye drop, some of the medication is absorbed into the rest of the body. Due to the possibility of increased side effects, dorzolamide should not be combined with another carbonic anhydrase inhibitor.
Other Eye Medications
If you take other eye medications, be sure to separate the dorzolamide dosage from those of the other medication(s) by at least 10 minutes.
There have been rare reports of serious drug interactions resulting in serious problems in people taking high-dose salicylates and oral carbonic anhydrase inhibitors. The risk of such problems is probably extremely small for dorzolamide, since it is given as an eye drop, especially if combined with low or normal doses of salicylates.