Bromday Warnings and Precautions

Before you use Bromday, it's important to know that this medication can sometimes cause bleeding problems, cornea problems, allergic reactions, and other issues. To help ensure a safe treatment with this eye drop, your healthcare provider will ask about your medical history and any other medications or supplements you are taking. Warnings and precautions with Bromday also apply to women who are pregnant or breastfeeding.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to using Bromday® (bromfenac ophthalmic solution) if you have:
  • A condition that causes you to bleed easily
  • Rheumatoid arthritis
  • Diabetes
  • Dry eyes
  • Any other eye condition
  • Had multiple eye surgeries in a short period of time
  • Any allergies, including to medications, foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Specific Precautions and Warnings for Bromday

Some warnings and precautions to be aware of prior to using this medication include the following:
  • This medication contains the inactive ingredient sodium sulfite, which could cause an allergic reaction in people with a sulfite sensitivity. Although the number of people who are actually sensitive to sulfites is thought to be low, people with asthma appear to have a higher risk. Sulfite sensitivity reactions can range from mild to severe, and may include a rash, hives, breathing problems, or, in serious cases, a life-threatening allergic reaction known as anaphylaxis. Seek immediate medication attention if you develop signs of an allergic reaction to Bromday.
  • Like other topical nonsteroidal anti-inflammatory drugs (NSAIDs), Bromday may slow down or delay healing. Taking Bromday with steroid eye medicines may increase the risk for healing problems (see Bromday Drug Interactions). Talk to your healthcare provider before using a steroid eye medicine during Bromday treatment. Also, let your healthcare provider know if your eye symptoms do not improve or become worse. 
  • People who are allergic to aspirin (acetylsalicylic acid) or other NSAIDs could also be allergic to Bromday. Let your healthcare provider know about all your drug allergies, including any allergies you have to nonprescription medications.
  • NSAID medicines can increase the risk for bleeding problems. There have been reports that NSAID eye medicines, such as Bromday, may increase bleeding of eye tissue after eye surgery. This risk may be higher in people with medical conditions that cause them to bleed easily or people who are taking other medicines that increase the risk for bleeding (see Bromday Drug Interactions). Bromday should be used with caution in such people.
  • Bromday can increase the risk for keratitis (inflammation of the cornea, the front part of the eye) or other cornea problems. These problems could be serious enough to result in loss of vision. Let your healthcare provider know right away if you experience any symptoms of corneal problems, including blurred vision, watery eyes, sensitivity to the light, or eye redness or pain, especially if these symptoms cannot be explained by your surgery alone, are severe, do not improve, or get worse.
  • Certain people may have a higher risk for developing serious cornea problems during Bromday treatment, including people with diabetes, rheumatoid arthritis, conditions that affect the surface of the eyes (such as dry eye syndrome), and people who had complicated eye surgeries or had multiple eye surgeries in a short period of time. Bromday should be used with caution in such people.
  • Using this medicine for more than 1 day before cataract surgery or for longer than 14 days after your surgery may increase your risk for developing serious cornea problems. Do not use this medicine for longer than your healthcare provider recommends.
  • This medication contains the preservative benzalkonium chloride, which can be absorbed by soft contact lenses. Do not wear contacts while using Bromday.
  • Bromday is a pregnancy Category C medication, which means it may not be safe for use during pregnancy, although the full risks are currently unknown (see Bromday and Pregnancy).
  • It is unknown if Bromday passes through breast milk. Therefore, if you are breastfeeding or plan to start, check with your healthcare provider before using this medication (see Bromday and Breastfeeding).

Bromday Eye Drop Information

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